HSDD patients don’t respond to their partner’s sexual signals, lose the desire for sex, or avoid sex altogether. Because they have little or no thoughts or fantasies about sex. Hypoactive Sexual Desire Disorder may be caused by Stress, Anxiety or depression, Tiredness, Menopause, Low sex hormone levels, Recent pregnancy, delivery, or breastfeeding, Sexual abuse or trauma in your past, Relationship problems, Issues with body image And Medical problems such as cancer, heart problems, diabetes, multiple sclerosis or bladder problems. Blood pressure medicines, antidepressant medicines, and feminizing hormone therapy, chemotherapy may also cause HSSD.