
Decreased magnesium levels in blood: Symptoms, Treatment & medicines
Decreased magnesium levels in the blood (hypomagnesemia)
Decreased magnesium levels in the blood, also known as hypomagnesemia. Hypomagnesemia is a medical condition in which the level of magnesium in the blood is lower than normal. Magnesium is an essential mineral that plays a critical role in many physiological processes in the body, including nerve and muscle function, regulating blood pressure and blood sugar, and maintaining healthy bones.

Causes of hypomagnesemia
There are several causes of hypomagnesemia, including:
- Inadequate dietary intake: A diet low in magnesium-rich foods such as green leafy vegetables, nuts, and whole grains can lead to a deficiency of magnesium.
- Malabsorption: Certain conditions that affect the absorption of nutrients in the intestine, such as celiac disease, inflammatory bowel disease, and chronic diarrhea, can lead to hypomagnesemia.
- Medications: Certain medications can interfere with the absorption or excretion of magnesium, including diuretics, antibiotics, and chemotherapy drugs.
- Chronic alcoholism: Alcohol abuse can lead to hypomagnesemia by reducing the absorption of magnesium and increasing its excretion through the urine.
- Kidney disease: Chronic kidney disease can lead to decreased magnesium excretion, resulting in a buildup of magnesium in the blood.
- Endocrine disorders: Certain hormonal imbalances, such as hyperthyroidism and parathyroid disorders, can affect magnesium levels in the blood.
- Pancreatitis: Inflammation of the pancreas can lead to decreased absorption of magnesium in the intestine.
- Hypercalcemia: High levels of calcium in the blood can lead to low levels of magnesium, as magnesium and calcium compete for absorption in the intestine.
Symptoms of hypomagnesemia
The symptoms of hypomagnesemia can vary depending on the severity of the condition. Mild to moderate hypomagnesemia may not cause any noticeable symptoms, while severe hypomagnesemia can lead to more severe symptoms. Some common symptoms of hypomagnesemia may include:
- Muscle cramps and spasms
- Weakness and fatigue
- Numbness and tingling in the extremities
- Abnormal heart rhythms (arrhythmias)
- Hypertension (high blood pressure)
- Mental confusion or disorientation
- Seizures
- Personality changes, such as irritability or anxiety
- Loss of appetite
- Nausea and vomiting
Diagnosis of hypomagnesemia
Diagnosing hypomagnesemia typically involves a combination of medical history, physical examination, and laboratory tests. Your healthcare professional may ask about your diet, medications, and symptoms, and perform a physical exam to look for signs of magnesium deficiency, such as muscle weakness or tremors.
Laboratory tests are used to confirm the diagnosis of hypomagnesemia and determine the severity of the deficiency. Blood tests can measure the level of magnesium in the blood, but this may not always be a reliable indicator of total body magnesium levels. Urine tests can also be used to measure magnesium excretion, which can provide additional information about magnesium status.
Treatment for hypomagnesemia
The treatment for hypomagnesemia typically involves magnesium supplementation, either orally or intravenously, depending on the severity of the deficiency. Your healthcare professional will determine the appropriate dosage and route of administration based on your individual needs.
For mild to moderate hypomagnesemia, magnesium supplements may be taken orally. Magnesium can be found in a variety of foods, including green leafy vegetables, nuts, and whole grains, so dietary changes may also be recommended.
For severe hypomagnesemia or in cases where oral supplementation is not effective or possible, intravenous magnesium may be administered in a hospital setting. This is typically reserved for patients with severe symptoms, such as arrhythmias or seizures.
Prevention of hypomagnesemia
The following are some ways to prevent hypomagnesemia:
- Eat a balanced diet: A balanced diet that includes magnesium-rich foods such as green leafy vegetables, nuts, and whole grains can help prevent magnesium deficiency.
- Limit alcohol consumption: Alcohol can interfere with magnesium absorption and increase magnesium excretion, leading to hypomagnesemia.
- Talk to your healthcare professional about medications: Some medications can interfere with magnesium absorption or increase magnesium excretion. Talk to your healthcare professional about any medications you are taking and whether they may affect magnesium levels.
- Manage underlying medical conditions: Certain medical conditions, such as kidney disease or gastrointestinal disorders, can lead to hypomagnesemia. Managing these conditions can help prevent magnesium deficiency.
- Consider magnesium supplements: If you are unable to get enough magnesium from your diet, your healthcare professional may recommend magnesium supplements. However, it is important to work with a healthcare professional to determine the appropriate dosage and monitor for any potential side effects.
- Avoid excessive intake of calcium supplements: High doses of calcium supplements can interfere with magnesium absorption and lead to hypomagnesemia. If you are taking calcium supplements, talk to your healthcare professional about the appropriate dosage and timing.
Medicines For hypomagnesemia
The following are some common medications used to treat hypomagnesemia:
- Oral magnesium supplements: These supplements come in various forms, including magnesium oxide, magnesium citrate, and magnesium glycinate. They are available over-the-counter or by prescription and are used to treat mild to moderate hypomagnesemia.
- Intravenous magnesium: In severe cases of hypomagnesemia or in cases where oral supplementation is not effective or possible, intravenous magnesium may be administered in a hospital setting. This is typically reserved for patients with severe symptoms, such as arrhythmias or seizures.